During the years in which he compiled a large section of the Codex Leicester in Florence (1504-1508), Leonardo was engaged in countless artistic, technical, and scientific activities, all characterized by the same pursuit of innovation.
The main locations of his most significant projects are highlighted in sequence on the map that portrays Florence and the Arno’s course through the city a few years before Leonardo’s return in 1501 after his long stay in Milan (1482-1500).